Enzyme subgroup,Atmosphere Air,Host Associated Animal,Cryosphere Cryosphere,Land Extreme env.Land,Ocean Extreme env.Ocean,Engineered Food,Land Freshwater,Host Associated Human,Host Associated Invertebrate,Engineered Mixed,Ocean Pelagic,Host Associated Photosynthetic organism,Ocean Sediment,Land Soil,Engineered Solid Waste,Engineered Surfaces,Engineered Synthetic,Engineered Wastewater Crop_protection,578,4451,1003,1706,2645,1740,7058,3214,1216,1182,6102,1352,1551,5813,2688,2503,1376,5327 Fertilizers,19,231,50,90,93,110,223,190,61,71,107,34,85,201,178,72,94,275 Animal_feedstock,892,17433,2256,2330,2727,4037,15120,11370,2334,1395,9933,3450,1310,15564,5926,4928,3221,13054 Agriculture_generic,11038,139089,23104,29972,49099,34772,182936,98339,27584,22050,154669,30203,26743,149075,56699,57154,30068,141043 Veterinary_medicine,67,440,222,194,326,155,640,295,204,126,577,191,210,572,275,353,205,563 Medical_generic,15381,195666,31448,42292,70588,45461,257583,124699,37252,30577,219787,42469,39898,216838,78855,83644,41281,200842 Drug_development,24451,384667,50430,70494,115772,78930,450080,253259,65894,52009,372795,63723,64706,339706,140954,130578,69711,340623 Pharmaceutical_generic,11271,192112,26233,35523,57796,39229,237219,124849,32779,24165,185604,28133,31681,165340,72814,63267,34048,176055 Molecular_biology,13792,218302,29595,42942,68102,46306,268785,140685,35285,29255,206475,38642,36831,207937,82559,78514,40965,211219 Paper_and_pulp,731,14914,1852,1728,2301,3007,12844,9152,1767,1135,8485,2766,912,13030,4795,4125,2662,10886 Detergent_generic,889,12754,2161,2406,3190,3137,15291,8582,1878,1368,10786,2837,1451,14602,5285,5220,2682,12546 Textile,641,9539,1453,1399,1939,2547,8756,5727,1321,843,6134,2162,745,8842,3275,3192,1911,7816 Food_industry,10252,142314,22111,29195,42566,35507,166949,99116,25216,19601,135835,29884,22918,145819,57740,56052,29328,136630 Starch_processing,520,6149,1140,1264,1317,1610,5331,4407,1150,789,3612,1303,710,4935,2628,2232,1452,5326 Juice,515,11362,1408,1506,1545,2588,8107,7456,1479,907,4979,2041,698,8312,3952,2865,2196,7847 Alcohol-Beverage_and_Brewing,1016,13198,1985,2634,3773,3147,14190,10852,2324,1855,10828,2680,2120,12710,5369,4978,2930,12282 Baking_industry,1124,9348,2381,2736,4571,3675,17721,6548,2377,1712,14324,3505,2371,16480,4465,6445,2665,13531 Dairy,626,12212,1463,1670,2612,2635,15964,8900,2337,1231,12531,1900,1342,10703,3815,4609,1871,12140 Degradation,4899,51202,9851,12352,18939,14872,72280,36892,10135,8558,58243,14766,11660,70311,22680,25489,12983,56375 Environment_generic,3116,26099,5539,6221,9897,8875,35846,19445,5814,4819,29872,8906,6636,38454,11597,14654,6791,29163 Other_Industry,4579,58796,8932,10069,14508,16622,63092,42427,10796,7486,49787,13196,8430,56471,22840,21664,12137,52262 Analysis,23339,388306,50815,70329,111693,77947,440917,257556,61730,48477,359650,62547,62687,338607,138351,126060,67725,335126 Diagnostics_generic,6595,114816,14120,20553,32846,24152,132311,77407,19450,15380,109083,17750,18046,93727,43131,37964,20391,102424 Biosensor_generic,3431,18890,5650,6667,10648,8474,33387,16411,5864,5395,31891,9048,6815,35379,10751,14466,6598,27753 Rubber,185,490,245,153,216,340,640,476,183,136,511,357,127,864,286,464,225,685 Cosmetics,304,3517,550,751,1507,1237,5821,2301,605,393,5084,996,600,4950,1142,1890,726,4274 Synthesis,33660,451488,72468,100578,152787,108108,564778,317094,83647,70489,467539,92335,87123,468891,189013,179577,93735,452704 Biopolymer-Plastic,2244,18724,4973,4568,9011,6455,34959,12496,4900,3516,31305,7399,4429,34134,8670,14469,5575,29089 Oil-Petroleum_recovery,268,7300,958,979,1049,1438,6015,4746,779,552,3692,1277,359,6506,2606,1785,1302,5207 Biofuel_production,239,3756,515,939,1076,955,4560,2363,635,491,2813,765,713,4339,2016,1242,773,3547 Energy_generic,409,6456,961,1049,1420,1869,6599,4057,949,677,4423,1610,627,7030,2524,2150,1370,5550